tert-Butyl N-(4-Methylphenyl)carbaMate
tert-Butyl N-(4-Methylphenyl)carbaMate
CAS: 14618-59-8
Molecular Formula: C12H17NO2
tert-Butyl N-(4-Methylphenyl)carbaMate - Names and Identifiers
tert-Butyl N-(4-Methylphenyl)carbaMate - Physico-chemical Properties
| Molecular Formula | C12H17NO2 |
| Molar Mass | 207.26888 |
| Density | 1.064±0.06 g/cm3(Predicted) |
| Melting Point | 92-92.8 °C |
| Boling Point | 255.3±19.0 °C(Predicted) |
| pKa | 13.87±0.70(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
tert-Butyl N-(4-Methylphenyl)carbaMate - Upstream Downstream Industry
| Downstream Products | p-Tolyl isocyanate TERT-BUTYL 4-CYANOPHENYLCARBAMATE |
tert-Butyl N-(4-Methylphenyl)carbaMate - Introduction
Tert-butyl P-benzyl carbamate is an organic compound with the chemical formula C13H19NO2. It is a white crystalline solid, soluble in organic solvents such as ether and chloroform, as well as in alkaline solutions of chlorides and cyanides.
t-butyl P-benzyl carbamate is mainly used as follows:
1. As a protecting group, it is commonly used in organic synthesis to protect amine compounds.
2. In the field of medicine, the compound can be used as a pharmaceutical intermediate and an active ingredient.
A method for preparing tert-butyl P-benzyl carbamates is generally obtained by reacting benzylamine with tert-butyl chloroformate. Benzylamine is first reacted with trimethylamine in the presence of sodium carbonate to give benzyl isocyanate. Benzyl isocyanate is then reacted with t-butyl chloroformate in the presence of lithium carbonate to give t-butyl P-benzyl carbamate.
Regarding safety information, tert-butyl P-benzyl carbamate is an organic compound and generally has certain toxicity. Care should be taken to avoid contact with skin and eyes and to maintain a well-ventilated working environment. In case of contact with skin or eyes, rinse immediately with water and seek medical advice. At the same time, in the use of the process to follow the laboratory safety procedures, and appropriate personal protective measures.
t-butyl P-benzyl carbamate is mainly used as follows:
1. As a protecting group, it is commonly used in organic synthesis to protect amine compounds.
2. In the field of medicine, the compound can be used as a pharmaceutical intermediate and an active ingredient.
A method for preparing tert-butyl P-benzyl carbamates is generally obtained by reacting benzylamine with tert-butyl chloroformate. Benzylamine is first reacted with trimethylamine in the presence of sodium carbonate to give benzyl isocyanate. Benzyl isocyanate is then reacted with t-butyl chloroformate in the presence of lithium carbonate to give t-butyl P-benzyl carbamate.
Regarding safety information, tert-butyl P-benzyl carbamate is an organic compound and generally has certain toxicity. Care should be taken to avoid contact with skin and eyes and to maintain a well-ventilated working environment. In case of contact with skin or eyes, rinse immediately with water and seek medical advice. At the same time, in the use of the process to follow the laboratory safety procedures, and appropriate personal protective measures.
Last Update：2024-04-09 21:11:58
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Product Name: tert-Butyl N-(4-Methylphenyl)carbaMate Visit Supplier Webpage Request for quotation
CAS: 14618-59-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 14618-59-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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